专利内容由知识产权出版社提供
专利名称：Shed antigen vaccine with dendritic cells
adjuvant
发明人：Jean-Claude Bystryn申请号：US10213388申请日：20020805
公开号：US20040022813A1公开日：20040205
摘要：The invention provides a method for producing a composition for use as avaccine for treatment or prevention of cancer, comprising collecting antigens released orshed by the type of tumor cell against which it is desired to prepare the vaccine;
preparing mammalian dendritic cells in a culture from a mammalian blood, bone marrowor other tissue sample by culturing the blood, bone marrow, or other tissue sampleunder conditions that cause differentiation and proliferation of dendritic cells; separatingdendritic cells from other cells in the culture; and exposing the dendritic cells to the shedantigens collected as described in paragraph a. above under conditions that result in thecombination of the shed cancer antigens or their fragments and the dendritic cells. Theinvention also provides compositions for administration as a vaccine for the treatment ofcancer, and other diseases.
申请人：BYSTRYN JEAN-CLAUDE
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