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专利名称：RECOMBINANT HUMAN ALPHA1-ANTITRYPSIN
发明人：BRINKMAN, Elisabeth, C., M.,HACK, Cornelis,
Erik,VAN DEN NIEUWENHOF, Ingrid
申请号：EP10716318.0申请日：20100420公开号：EP24215B1公开日：20151111
摘要：The present invention relates recombinant human α1-antitrypsin (rhAAT)comprising N-linked glycans, wherein at least 10% of said N-linked glycans are tetra-antennary glycans; and the degree of capping with sialic acid on said N-linked glycans(Z/A) is at least 50%.The invention further relates to rhAAT for use as a medicament, inparticular for use in the prevention and/or treatment of a disease associated with AATdeficiency, and/or a disease involving neutrophil-mediated tissue damage.
申请人：CRUCELL HOLLAND BV
地址：NL
国籍：NL
代理机构：Manten, Annemieke
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