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ANALYSIS METHOD

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专利名称:ANALYSIS METHOD发明人:NILSSON, FREDRIK申请号:EP2005006866申请日:20050622

公开号:WO2006002841A3公开日:20060420

摘要:A method for quantitative measurement using mass spectroscopy of a peptideor peptides generated from one or multiple analyte proteins by enzymatic or chemicalcleavage, the method comprising the step of exposing together the sample to beanalysed and one or multiple mass-labelled peptide internal standard precursors toenzymatic or chemical cleavage so as to generate from said precursor one or multiplemass-labelled peptide internal standards, wherein the mass-labelled peptide internalstandard precursor comprises an extension of a least one amino acid N-terminal to theN-terminus of the N-terminal-most mass-labelled peptide internal standard generatedtherefrom, and an extension of at least one amino acid C-terminal to the C-terminus ofthe C-terminal-most mass-labelled peptide internal standard generated therefrom.

申请人:BIOINVENT INTERNATIONAL AB,NILSSON, FREDRIK

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